From ACS Central Science Imaging Mass Spectrometry Reveals Crosstalk between the Fallopian Tube and the Ovary that Drives Primary Metastasis of Ovarian Cancer This is a great project and a great paper by Laura Sanchez group! A worthwhile reading. From Chemical Reviews Production and Synthetic Modifications of Shikimic Acid From the Journal of Natural Products […]
From the Journal of Natural Products Bromopyrrole Alkaloid Inhibitors of the Proteasome Isolated from a Dictyonella sp. Marine Sponge Collected at the Amazon River Mouth From Nature Major publishers sue ResearchGate over copyright infringement – Elsevier and the American Chemical Society say that the academic-networking website violates US copyright law. University tenure decisions still gloss over […]
From ACS Chemical Biology Molecular Basis for Autocatalytic Backbone N-Methylation in RiPP Natural Product Biosynthesis From Science Vaccines Against a Vanishing Virus? From the Journal of Medicinal Chemistry Two Decades under the Influence of the Rule of Five and the Changing Properties of Approved Oral Drugs Structure-Based Drug Design and Identification of H2O-Soluble and Low […]
From Science magazine A New Antibiotic? Yes, Please From the Journal of Natural Products Active Natural Product Scaffolds against Trypanosomatid Parasites: A Review Dinghupeptins A–D, Chymotrypsin Inhibitory Cyclodepsipeptides Produced by a Soil-Derived Streptomyces Nematicidal Cyclic Lipodepsipeptides and a Xanthocillin Derivative from a Phaeosphariaceous Fungus Parasitizing Eggs of the Plant Parasitic Nematode Heterodera filipjevi Diversity-Oriented Synthesis […]
Some posts will be dedicated to news from the Brazilian press on science and related subjects. I apologize to people who cannot read in Portuguese. Novo acelerador de partículas do país terá R$ 70 mi para 1ª volta de elétrons – Sirius, em Campinas, ainda precisa de R$ 510 milhões para conclusão, mas teste deve ser […]
From Organic Letters Crystalline Sponge Method Enabled the Investigation of a Prenyltransferase-terpene Synthase Chimeric Enzyme, Whose Product Exhibits Broadened NMR Signals Computationally Assisted Assignment of the Kadsuraols, a Class of Chemopreventive Agents for the Control of Liver Cancer Total Synthesis of Repraesentin F and Configuration Reassignment by a Gold(I)-Catalyzed Cyclization Cascade Sophalines E–I, Five Quinolizidine-Based […]
From Angewandte Chemie International Edition Total Synthesis of C30 Botryococcene and epi‐Botryococcene by a Diastereoselective Ring Opening of Alkenylcyclopropanes Synthesis, Structural Reassignment, and Antibacterial Evaluation of 2,18‐Seco‐Lankacidinol B Editorial – Empowering Students to Innovate: Engagement in Organic Chemistry Teaching I recently had the pleasure of competing for the Robert Foster Cherry Award for Great Teaching given biennially […]
Toward Understanding the Chemistry and Biology of 1-Deoxy-d-xylulose 5-Phosphate (DXP) Synthase: A Unique Antimicrobial Target at the Heart of Bacterial Metabolism Synthetic Lava Brings Eruption into the Lab Molecular Basis for Olefin Rearrangement in the Gephyronic Acid Polyketide Synthase Biochemical and Structural Characterization of TtnD, a Prenylated FMN-Dependent Decarboxylase from the Tautomycetin Biosynthetic […]
Reconstitution of Enzymatic Carbon–Sulfur Bond Formation Reveals Detoxification-Like Strategy in Fungal Toxin Biosynthesis Mycobacterial MenJ: An Oxidoreductase Involved in Menaquinone Biosynthesis Estudo traz novas pistas sobre sofisticada sociedade que ergueu enigmáticas estátuas gigantes da Ilha de Páscoa – A maior parte dos quase 900 moais mede de 4 a 6 metros de altura Céticos do clima […]
Reportagem publicada no jornal Folha de São Paulo comenta sobre o “odor da chuva” e alguns de seus principais componentes, que já estão sendo utilizados na composição de perfumes, como a geosmina, produzida por uma actinobactéria. Por que o cheiro da chuva é tão bom? – Bactérias, plantas e até trovoadas têm influência no aroma de […]
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