Among the articles published in 2018 by our group, a new review titled Natural Products from Marine Invertebrates and Microorganisms in Brazil between 2004 and 2017: Still the Challenges, More Rewards covers the research by Brazilian investigators on marine natural products from 2004 until 2017. It is an update of our previous review on the same subject, published in 2004 in the Journal of Natural Products. The fine work performed by the PhD student Laura P. Ióca and by Dr. Karen J. Nicácio comprehensively discuss the research on isolation, structure analysis, biological activities and biosynthesis. Total syntheses of marine natural products performed by Brazilian synthetic chemists is discussed as well, including research by Luiz Carlos Dias (UNICAMP), Ronaldo A. Pilli (UNICAMP), Carlos Roque Duarte Correia (UNICAMP), Fernando A. S. Coelho (UNICAMP), Luiz Cláudio de Almeida Barbosa (UFMG), the later Luiz Fernando da Silva Júnior (USP) and Ângelo da Cunha Pinto (UFRJ). The review clearly shows the growing interest on marine natural products in Brazil during the last 13 years, in particular by the chemistry of marine microbes (bacteria and fungi). The review is one of the articles of the prestigious Journal of the Brazilian Chemical Society special issue dedicated to the IUPAC 2017 meeting, held in São Paulo, Brazil. We thank the JBCS editors for the very kind invitation to submit a manuscript to this JBCS special issue. Read the complete open access article here.