The article “Clathriamide, an hexapeptide isolated from the marine sponge Clathria (Clathria) nicoleae” results of part of Vitor F. Freire PhD project on the investigation of marine sponge metabolites. The sample of Clathria (Clathria) nicoleae was provided to us by the Rio de Janeiro research team at Jardim Botânico, Fernando C. Moraes, Wladimir C. Paradas, Leonardo T. […]
After a while not posting for too many reasons, we start 2020 including the activities of 2019 which have not been mentioned here. The first is the review “Approaches for the isolation and identification of hydrophilic, light-sensitive, volatile and minor natural products”, published in Natural Product Reports. This was an invited review by the guest […]
This post had to be written a while ago. Professor Koji Nakanishi’s death meant very much to the natural products chemistry community. Needless to say, his achievements are beyond words. Two of the perhaps less-known facts of Professor Nakanishi’s career are worth of mention. The first is his 1962 book on infrared spectroscopy, with a […]
One project whose results were published in 2018 and has not been mentioned here was the discovery of anti-malarial activity of pseudoceratidine and synthetic derivatives. This project started some years ago when a MSc student Ivan Severo started to work on a sample of the sponge Tedania brasiliensis, endemic to Brazil, and isolated pseudoceratidine. Unfortunately […]
We are pleased to have new researchers in the QOSBIO research group at the Universidade de São Paulo, São Carlos. Dr. Camila M. Crnkovic joined the group earlier this year. Dr. Camila was awarded with a PhD degree at the University of Illinois, Chicago School of Pharmacy, under the supervision of Professor Jimmy Orjala. Dr. Camila […]
A very kind invitation by Professor Simon Gibbons to us was to prepare a review for the highly reputed series Progress in the Chemistry of Organic Natural Products. Formerly known as Fortschritte der Chemie organischer Naturstoffe, this series features comprehensive reviews on all aspects of natural products chemistry, biochemistry, technologies, theoretical and practical advances, biosynthesis, particular […]
The recent investigation of new bromopyrrole alkaloids by a former MSc. student, Renata Torres, resulted in the discovery of 4-debromooroidin (1), 4-debromougibohlin (2), 5-debromougibohlin (3) and 5-bromopalau’amine (4) from the MeOH extract of the sponge Dictyonella sp. These new alkaloids were isolated along with the known hymenidin (5) and (+)-monobromoisophakellin (6). Curiously, the bromination pattern of compounds […]
Very glad to have been recognized by the Phytochemistry Letters editorship as outstanding reviewer. Good quality and highly professional peer-review is central to science. Very few other human activities benefit of such a direct feedback that contributes to enhance the quality of research and capacity building. Thanks to Professor Simon Gibbons and to the editorial […]
Among the articles published in 2018 by our group, a new review titled Natural Products from Marine Invertebrates and Microorganisms in Brazil between 2004 and 2017: Still the Challenges, More Rewards covers the research by Brazilian investigators on marine natural products from 2004 until 2017. It is an update of our previous review on the same […]
From ACS Chemical Biology Monoamine Biosynthesis via a Noncanonical Calcium-Activatable Aromatic Amino Acid Decarboxylase in Psilocybin Mushroom
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